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The Unhealthiest Pizzas in America—Ranked!

We did some digging and discovered the most caloric, fattiest, and sodium-filled slices in the nation.
The Unhealthiest Pizzas in America—Ranked!
Courtesy of Uno Pizzeria & Grill

Pizza may have its roots in Italy, but American pizzerias have successfully found a way to make a seemingly harmless food into a caloric monster. Shocking, we know. So, we decided to showcase some of the unhealthiest slices of pizza offered at some of the most beloved pizza chains in the U.S., in an attempt to reveal which slices you should steer clear of. Trust us, you'll think twice before grabbing that second (or third) slice of one of these unhealthiest pizzas in America.

Methodology: In order to identify the unhealthiest pizza slices in America, we compiled a list of the most caloric slices from some of the most popular pizza chains nationwide. The pizza slices with the most calories, in most cases, also have the highest total fat, saturated fat, and sodium contents as well. To break ties, we chose the slice of pizza that had a greater amount of at least two of the following: total fat, saturated fat, and sodium. We only considered the top three most unhealthy pizza slices at each restaurant to ensure we represented a diverse range of restaurants on this list. Only slices from the restaurants' large size pies were considered. In the case of Little Caesars, we had to manually calculate the nutritional information for just one pizza slice, as nutrition information was only provided for the whole pie. We excluded stuffed crust pizzas from this ranking.

Now, here are the 16 unhealthiest large pizza slices in the country, ranked from the least bad to the unhealthiest of them all.

From Bad to Absolute Worst

16

Domino's ExtravaganZZa Pizza

Extravaganzza pizza
Courtesy of Domino's

Nutrition (per slice, 14-inch large pizza): 390 calories, 18 g fat (7 g saturated fat, 0 g trans fat), 970 mg sodium, 38 g carbs (2 g fiber, 3 g sugar), 17 g protein

One large slice of Domino's ExtravaganZZa pizza amounts to just under 400 calories. This slice of pizza, which is stacked with meat, including Italian sausage, beef, and pepperoni, has nearly as many calories as two slices of CiCi's Meat Eater pizza. That better be the only slice you eat from this pie! One slice of this pizza also costs you nearly 1,000 milligrams of sodium, which is almost half of your daily allotment. For context, the American Heart Association recommends you consume no more than 2,300 milligrams of sodium per day.

15

Papa John's Pepperoni, Sausage, and Six Cheese Pizza

papa johns pepperoni sausage six cheese pizza
Courtesy of Papa John's

Nutrition (per slice, 14-inch large pizza): 390 calories, 20 g fat (9 g saturated fat, 0 g trans fat), 920 mg sodium, 36 g carbs (1 g fiber, 3 g sugar), 16 g protein

The name of this pizza pie is a dead giveaway of what's on this large slice of pizza. Pepperoni, sausage, and—as the Papa John's website states—a generous six-cheese blend. That extra cheese is likely what contributes to the slightly higher total fat and saturated fat contents than what's in a slice of Domino's ExtravaganZZa, which comprises an equal amount of calories.

14

Little Caesars' DEEP!DEEP! Ultimate Supreme Pizza

little caesars deep deep ultimate supreme pizza
Courtesy of Little Caesars

Nutrition (per slice, 14-inch pizza): 393 calories, 17 g fat (7.5 g saturated fat, 0.4 g trans fat), 840 mg sodium, 42 g carbs (3 g fiber, 3 g sugar), 18 g protein

Little Caesars' DEEP!DEEP! Ultimate Supreme is one of the worst pizzas you can buy. Why? Not only is one slice just seven calories below 400, but it also houses a whopping 42 grams of carbs. That's like eating a little more than two and a half pieces of Pepperidge Farm's Italian White bread. So, imagine you eat two of these slices. That's the same as eating over five pieces of bread in one sitting—without even adding on sauce, toppings, and cheese yet.

13

Domino's Cali Chicken Bacon Ranch Pizza

Cali chicken bacon ranch pizza
Courtesy of Domino's

Nutrition (per slice, 14-inch large pizza): 400 calories, 20 g fat (7 g saturated fat, 0 g trans fat), 880 mg sodium, 36 g carbs (2 g fiber, 2 g sugar), 17 g protein

A slice of this bacon and chicken topped pizza crashes through the 400 calorie mark. If you're ordering a large-sized pizza to feed a crowd of friends, but trying to watch your calorie intake, just order the large regular cheese pizza from the pizza chain. Each slice clocks in at 290 calories and has only 10 grams of total fat and five grams of saturated fat. While it's still high in calories for one slice of pizza, it is a better option even though that does mean you have to say goodbye to the toppings.

RELATED: The easy way to make healthier comfort foods.

12

Pizza Hut's Supreme, Large Original Pan Pizza

Pizza hut supreme pizza
Pizza Hut/Facebook

Nutrition (per slice, 14-inch large pizza): 400 calories, 20 g fat (7 g saturated fat, 0.5 g trans fat), 740 mg sodium, 37 g carbs (2 g fiber, 2 g sugar), 16 g protein

It's no wonder why Pizza Hut coins this pizza pie the Supreme—just one large slice contains as many calories as you'll find in 33 Totino's Pepperoni Snack Bites. For a healthier large pizza option at Pizza Hut, choose the Veggie Lover's Hand Tossed pie. Just one slice of this veggie-stacked option contains 260 calories—much less than the 400 the Supreme packs.

11

Papa Murphy's Bacon Cheeseburger Pizza

papa murphys bacon cheeseburger pizza
@PapaMurphysUAE/Twitter

Nutrition (per slice, 14-inch large pizza): 420 calories, 20 g fat (10 g saturated fat, 0 g trans fat), 1,340 mg sodium, 37 g carbs (0 g fiber, 8 g sugar), 20 g protein

The tenth unhealthiest pizza you can buy nationwide is Papa Murphy's Bacon Cheeseburger pizza. To better understand just how caloric this dish is, a cheeseburger with bacon at McDonald's contains 360 calories…which is 60 calories less than this single slice. In fact, it would be better to eat the fast food burger, because it has lower sodium (coming in at 920 milligrams) and offers an equivalent amount of protein.

10

Little Caesars' DEEP!DEEP! Dish 3 Meat Treat Pizza

little caesars deep deep dish 3 meat treat pizza
Courtesy of Little Caesars

Nutrition (per slice, 14-inch pizza): 421 calories, 21 g fat (9 g saturated fat, 0.4 g trans fat), 874 mg sodium, 40 g carbs (2 g fiber, 2 g sugar), 19 g protein

This thick crust pizza pie is stacked high with three kinds of meat: pepperoni, Italian sausage, and bacon. One slice packs one gram more of saturated fat than what one Hershey's chocolate bar (43 grams) contains. At least with the chocolate bar you're eating about 200 less calories.

9

Pizza Hut's Pepperoni Lover's, Large Original Pan Pizza

pizza hut pepperoni lovers pizza slice pulled out of pie
Pizza Hut Zimbabwe/Facebook

Nutrition (per slice, 14-inch large pizza): 440 calories, 24 g fat (9 g saturated fat, 0.5 g trans fat), 850 mg sodium, 37 g carbs (3 g fiber, 2 g sugar), 19 g protein

This pizza pie lures all of the pepperoni lovers of the world, but it comes at a price to your health. If you really love pepperoni but don't want to lose nearly 450 calories over it, you could opt for the normal pepperoni large original pan for 370 calories, 6 grams of saturated fat, and 680 milligrams of sodium. It's not the best option you could eat, but it's the lesser of two evils here.

8

Pizza Hut's Meat Lover's, Large Original Pan Pizza

Pizza hut meat lovers pizza
@PizzaHut/Twitter

Nutrition (per slice, 14-inch large pizza): 470 calories, 27 g fat (10 g saturated fat, 0.5 g trans fat), 970 mg sodium, 37 g carbs (2 g fiber, 2 g sugar), 19 g protein

It's pretty obvious where this gargantuan slice of pizza gets its calories from, yes? Pizza Hut's Meat Lover's pizza has got it all—pepperoni, Italian sausage, ham, bacon, pork, and beef. One large slice of this pizza contains more calories and total fat than a double cheeseburger at McDonald's.

7

Mellow Mushroom's Great White Pizza

mellow mushroom great white pizza
Mellow Mushroom/Facebook

Nutrition (per slice, 16-inch large pizza): 490 calories, 28 g fat (9 g saturated fat, 0 g trans fat), 1,010 mg sodium, 50 g carbs (3 g fiber, 4 g sugar), 22 g protein

Um, 480 calories for a cheese pizza? That's out of this world for a pie with no toppings. Mellow Mushroom, what kind of cheese are you layering this pizza with over there? It turns out, this option contains a lot more than just your standard shredded mozzarella. Here's what the site says is on the caloric slice: "Olive oil and garlic base with sun-dried roasted tomatoes, provolone, feta cheese, seasoned ricotta, fresh basil, mozzarella, roma tomatoes, and onions." Did you drool? Hopefully, you didn't, because one slice makes up about a quarter of your daily calories—yes, that is only for just one slice!

6

Mellow Mushroom's Mighty Meaty Pizza

mellow mushroom mighty meaty pizza
Courtesy of Mellow Mushroom

Nutrition (per slice, 16-inch large pizza): 520 calories, 26 g fat (9 g saturated fat, 0 g trans fat), 1,340 mg sodium, 46 g carbs (2 g fiber, 2 g sugar), 30 g protein

Are we beginning to see a trend here? Pizzas that are loaded in meat inevitably contain more calories, fat, and sodium. Mellow Mushroom's Mighty Meaty pizza is the perfect example with pepperoni, sausage, ground beef, ham, and bacon, which hikes up the calorie count to over 500 for a single slice.

5

Mellow Mushroom's Buffalo Chicken Pizza

mellow mushroom buffalo chicken pizza with ranch and buffalo sauce swirl
Scotty C./Yelp

Nutrition (per slice, 16-inch large pizza): 550 calories, 34 g fat (9 g saturated fat, 0 g trans fat), 1,640 mg sodium, 48 g carbs (2 g fiber, 4 g sugar), 28 g protein

Mellow Mushroom strikes again with yet another high-in-calories pizza. Not only does the Buffalo Chicken variety cost you nearly 550 calories per large slice, but it also costs you 1,610 milligrams of sodium. For perspective, that's as much sodium that's in about 17 Snyder's Pretzel Rods.

4

Sbarro's NY Pepperoni Slice

slice of pepperoni pizza from sbarro on printed paper and red tray
Kim T./Yelp

Nutrition (per XL slice, 17-inch large pizza): 552 calories, 23 g fat (10 g saturated fat, 1 g trans fat), 1,459 mg sodium, 61 g carbs (5 g fiber, 9 g sugar), 25 g protein

Technically, this is an extra large pizza slice, but we thought we would toss this classic slice of pepperoni in the lineup because of how caloric it is. Not to mention, if you've ever popped into a Sbarro (it's a staple at just about any major mall) you'll notice that it's the only size you can get, which subjects you to more calories, saturated fat, and sodium, without giving you a choice to opt for a smaller slice. Yikes!

3

Uno Pizzeria and Grill's Chicago Classic Pizza

uno pizzeria grill chicago classic pizza slice
Courtesy of Uno Pizzeria & Grill

Nutrition (per slice, 12-inch pizza): 830 calories, 59 g fat (18 g saturated fat, 0 g trans fat), 1,620 mg sodium, 42 g carbs (2 g fiber, 3 g sugar), 34 g protein

Uno's Chicago Classic is the chain's attempt at emulating Chicago's deep dish pizza. However, be warned, because this pizza is packing in calories—over 800, to be specific. What's even more concerning is the saturated fat content at 18 grams. The American Heart Association recommends that you consume no more than 13 grams of saturated fat in one day to prevent heart disease. With this slice of pizza, you get your daily amount and then some. It better be worth sacrificing your entire day's worth in just one sitting.

2

Uno Pizzeria and Grill's Chicago Meat Market Pizza

Uno chicago deep dish meat market pizza
Uno Chicago Grill

Nutrition (per slice, 12-inch pizza): 870 calories, 60 g fat (18 g saturated fat, 0 g trans fat), 1,850 mg sodium, 45 g carbs (2 g fiber, 4 g sugar), 35 g protein

There's a reason why this pizza is called the Meat Market. Topped with layers of steak, meatballs, sausage, pepperoni, and mozzarella, this slice of pizza is chock-full of sodium. In fact, you'd have to drink more than two cups of Swanson's Chicken Broth to achieve the same amount of sodium.

1

Uno Pizzeria and Grill's Chicago Fire Pizza

Unos chicago fire deep dish pizza
@UnosChicagoGrill/Twitter

Nutrition (per slice, 12-inch pizza): 950 calories, 66 g fat (18 g saturated fat, 0 g trans fat), 1,550 mg sodium, 52 g carbs (2 g fiber, 2 g sugar), 35 g protein

Uno Pizzeria & Grill snags the top three spots for the country's unhealthiest slices of pizza. Clocking in at a near 1,000 calories for just one 12-inch slice of deep dish pizza is the Chicago Fire. What could possibly make this slice of pizza so dense in calories? Well, it's topped with chicken tenders and generously sprinkled with gorgonzola, cheddar, and mozzarella, and then heavily drizzled in bleu cheese dressing. That just about explains it, don't you think?

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Cheyenne Buckingham
Cheyenne Buckingham is the news editor of Eat This, Not That!, specializing in food and drink coverage, and breaking down the science behind the latest health studies and information. Read more
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